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WARNING be aware of H.I.T. IF YOU ARE ON CLEXANE PLEASE MAK...

Posted at 8:50 AM on Mar 04, 2008 by jillorrell, #27705
WARNING be aware of H.I.T. IF YOU ARE ON CLEXANE PLEASE MAKE SURE THE DOCTORS CHECK YOUR PLATELET LEVELS BEFORE STARTING THIS DRUG.DO NOT BE AFRAID OF ASKING AS THIS IS STATED IN GUIDELINES. THE GUIDELINES SUGGEST IF YOUR PLATELET COUNT FALLS 50% FROM WHAT IT WAS BEFORE YOU STARTED THE TREATMENT THEN H.I.T. SHOULD BE SUSPECTED AND ALL FORMS OF HEPARIN SHOULD BE DISCONTINUED AND AN ALTERNATIVE ANTICOAGULANT BE USED. THIS IS VERY IMPORTANT; PLEASE DO NOT TRUST YOUR DOCTOR TO AUTOMATICALLY DO THESE TESTS. WE TRUSTED MY GRANDMOTHERS DOCTORS, THEY DID PART OF THE TESTS BUT FAILED TO ACT ON THE RESULTS!!!!! My grandmother died from heparin induced thrombocytopenia (HIT). This is an adverse reaction to the drug Clexane. Guidelines suggest platelet count should be monitored, unfortunately the hospital Doctors did not monitor her blood whilst she was on this drug. A 50% fall in platelet count should have alerted Doctors to act on their findings and discontinue the drug, instead they carried on giving it to her for a further 6 days. Her symptoms were as follows; itchy drowsy bruises nausea vomiting diarrhea Because her reaction to Clexane had gone unnoticed she was still being given this drug her symptoms became worse they were as follows; Black bruises (necrosis) gastrointestinal haemorrhage spontaneous bruising slurred speech confusion falling platelet count When the Doctors discovered the internal bleeding they stopped the Clexane but did not offer her an alternative anticoagulant and her symptoms after this were as follows; Deep vein thrombosis, arterial thrombosis, she was still hemorrhaging, her platelets fell to 5 and her HB fell to 6.9 INR was normal. She was transfused with platelets and red blood cells and then died. (Clexane heparin induced thrombocytopenia) is on her death certificate AFTER A FOUR YEAR BATTLE FOR AN INQUEST INTO HER DEATH! My research has led me to believe that most Doctors believe HIT is very rare and they don't bother to check for this condition, if the doctors had checked her blood test and realized a sudden 50% fall in her platelet level was more significant than the actual platelet count itself , then she would not have died.The 50% drop was a serious side effect of this drug. PLEASE ASK YOUR DR TO CHECK AND TELL HIM/HER TO CHECK IF YOU HAVE GOT BETWEEN 30-50% DROP IN PLATELETS THEN MAKE SURE YOUR DOCTOR KNOWS WHAT HE IS DOING. Jill (Lancashre UK)
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Reply about 1 year ago on Mar 14, 2008 by kelleymarie, #5526

i ve had a dvt for 6 months since i had my son i found out a wee ago that im pregnant andnow on clexane 2twice aday im scared of any side effects and im scared that it ccould kill me. when doctors first noticed somethink with my blood in last pregnacny they never done ny think if hey did i was told by another doctor i woiuld of been ok now

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Reply about 1 year ago on Jul 19, 2008 by spearoelo, #10269

When I was given Clexane in hospital the effects were as follows immediately after the injection.
Raised heart rate
Raised blood pressure
Feeeling hot
Light headedness
Dry throat
Pounding headache
There does not seem to be any information on this reaction.

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Reply 4 months ago on Jul 11, 2009 by gilliane, #21392

I was given Clexane before an operation to remove my Gall Bladder by keyhole surgery in August 2008.
After the surgery, everything seemed normal, but I collapsed on the first trip out of bed. The next day I didn't feel at all well. I stayed in hospital a few extra hours & then was released. At night, when I got into bed I could hear my own heart thumping. I couldn't sleep for it. The next day I felt very weak. A friend came & she said I looked terrible (not at the time, but after the event). By night time, still having this thump thump thump in my chest I made a phone call to NHS Direct to ask their advice. They told me to go back to hospital A & E asap.
They examined me thoroughly & the A & E Doc thought it was all post operative stuff. However, he decided to take a blood test just to be on the safe side. After a 2 hour wait he came back with 2 nurses & I was admitted. My blood count had dropped to 7.4. By the time I got onto a ward my blood count was 7 exactly.
The consultant who operated said Clexane had thinned my blood too much. The blood had gone into the chest--none of it had leaked out of the wound or into my digestive system. If it had I would have realised I was bleeding.
I'm still not sure I've been told the truth about this.
I had 3 units of blood & a unit of plasma (because there wasn't a medic on the ward who could put the blood in during the night--beggars belief). I wonder whether I should wear some sort of bracelet to make sure I'm never given this again?

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