My friend has been taking Lisinopril for several years,then sudde...

Maxine...your post is very intersting to me. I have been on Lisinopril for almost 10 years now for minor HTN. A few months after beginning Lisinopril I began having swelling in my lips and slight swelling in my tongue. I figured I was probably allergic to something but did not give the medication a thought. Approx 1 year after taking it, I had a severe allergic reaction that caused my tongue to swell to the point my tongue was sticking out of my mouth and I was having difficulty breathing. I drove myslef to my family Dr and was treated with epinephrene and steriods. The Dr had the crash cart ready in case I "punched out." After about 3 hours the swelling subsided. My Dr and I tried for several weeks to determine the trigger for the episode. There didn't seem to be any specific reason for it.

Fast forward almost 9 years to last week. I have been battling severe sinus conditions for about 10 years or so. I have now had 5 sinus surgeries to remove severe polyp growth in my sinuses. My ENT finally decided I needed to see an allergist. After going over my history and my medications I told him about the swollen tongue episode. He immediately told me that it was due to the Lisinopril. He told me ACE Inhibitors are notorious for those types of reactions and it could happen again at any time, even thought it has been over 9 years since the only episode. He told me he would contact my GP and advise him to take me off the Lisinopril and prescribe something else.

Like many others on this site I too have experienced many symptoms that have not been properly explained. I am just wondering how many could be attributed to Lisinopril. Based on many of the side effects I have read here, some or all can be attributed to the Lisinopril, including the sinus conditions I have been battling for the last 10 years. My GP and I will be having a very serious talk at my next visit.