I was just prescribed the Imitrex nasal spray. I took it for the first time today. The first thing that happened was my nose felt like it was on fire then i had a horrible bitter taste in my mouth and the back of my throat. About 10mins after i took it i throw up and my stomach started to hurt. Plus the bitter taste was still there and nothing but time made it go away. My headache went away true enough but I would rather suffer a migraine then go through that again. And my headache came back not too long afterwards.