I have been on hydrochlorothiazide for about a year now, 25mg. daily. In the last 6 months I have noticed that I have very dry mouth in the evening especially, with a feeling that I have post nasal drip. It feels like mucus is between my nose and throat and there is no way I can swallow it...it never seems to go down. I have it until I go to bed, then it seems to disappear until the next evening. My nose is clear though. I also notice I am more jittery than usual during the day, and I have very sleepless nights. I seem to toss and turn all night long and don't feel rested in the morning. I am 66 years old.