I had no idea an antibiotic could cause such side effects until I visited this site. I have taken Levaquin twice in the past 2 months for chronic sinusitis. First time for 10 days (250 mg) and then couple of weeks later for 21 days (500 mg). I don't think it is gone yet. I complained to my husband of extreme joint pain, pain in my ankles and extreme fatigue. He said I bet it is that antibiotic you are taking and I just kind of brushed him off. However, when I mentioned it to a friend who has had many sinus problems she said I better check it out on the Internet. Sure enough I see others who have had similar problems. I work nights so I do have different sleep patterns but have never been one to require a lot of sleep but lately I can't seem to get enough sleep. I have not taken it for about 5 to8 days and wonder when my symptoms will start to go away.
I, too, am allergic to penicillin and sulfa so have tried many different antibiotics but never had a reaction like this. It is horrible to have this much pain. I will definitely be telling my doctor about my reaction to this antibiotic. I, too, was never given any warning about the possible reactions to this but was told not to take it with other products like calcium. My patient advisory leaflet did mention to advise my doctor if I had tendon, joint or muscle pain but I didn't make the connection of this type pain. Guess I should have been smarter.