I am a 66 year old female with mild hypertension successfully treated with 25 mg HCTZ for over 10 years. In January 2008 I developed sinusitis and ended up in the hospital for a week exceedingly high BP and an electrolyte imbalance. Initially the MD wanted to give me Lisinopril, but I told him that there is a hx of family sensitivity to the drug. Both my mother and brother had developed a severe cough and had to stop Lisinopril. He prescribed something else. It's now 2 months since my acute illness and they can't get my BP under control. I told my MD that I would be willing to try Lisinopril since the cough from my sinus infection is now gone. I didn't want to rule out using it just because of a family hx. Maybe I would react differently? I am already on 2 BP meds and Lisinopril made it #3. I took 2.5 mg Lisinopril and for 3 days felt wonderful. My BP was terrific. I suddenly developed severe acid indigestion which kept me awake all night. The next day I had a dry cough which would make me me gag. Then I developed non-stop belching, nonspecific stomach discomfort, and loose stools. I felt "not quite all there". My BP has been terrific. I just called my MD and she will prescribe something else. I asked her, taking only 2.5 mg, if it's possible to develop side effects in only 3 days and she said yes. Wish me luck as I try my new 3rd BP medicine.