Hi, I have been taking Doxycycline for a month for Lymes disease. I have not had the reflux, but my doctor gave me a couple rules to prevent it, because it can cause esophogitis. First rule is not to take it after 7pm. The second rule is to not lie down for a 1/2 hour after taking it. I also take it on a full stomach, otherwise I will become extremely nauseated. Good luck, and I hope you feel better soon!
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