Taking doxycycline 100mg for almost 1 week now due to bronchitis and noticed an immediate tingling in my lips and hands. My hands are extremely sensitive to tap water (cold), putting them in the refridgerator to take out something and heat. At night when I'm laying around cuddled up in a blanket my hands are on fire and red. I thought it was the blanket. It's the strangest feeling and uncomfortable. It lasts all day but gets worse at night. I hate pills.