I have been taken bactrim for 1 day and feel awful. I came home from work and got straight in the bed. I was feeling real tired,had chills and all kinds of body aches from my head down to my legs. And what got me, is that both of my wrists hurt so bad till I can't lift anything. Also having chest pains and elevated heart rate. I just got up from lying down after work and thought, I will search the side effects for bactrim on the internet. I'm glad I did. I wil not take this anymore.