I was using Restasis, as well as Methotrexate, to help relieve the discomfort of dry eye and scleritis; however, I believe after six months of using Restasis, there has been progressive redness and extremely painful episodes. I believe I have discovered that the Restasis was actually exacerbating the scleritis!! I discontinued the use of the Restasis, and magically, my eyes, which have been continually red and terribly painful for at least six months, have cleared! Not sure yet if it was actually the Restasis that was causing my scleritis to worsen, but if my eyes continue to stay clear, I will not use the Restasis again.