Added Wellbutrin 150mg to my daily Lexapro 10mg for only three days now and I can tell the difference. I'm energetic but feel like I'm moving slow. I am very focused but short memory. Heart burn, yes, not bad - yuck. Very snappy with my honey though, hope this goes away quickly. How long do these side effects last? Does anyone ever plan to use this stuff for a short therapy and then get off - or do I seriously need to think about being on this therapy forever. Makes me wonder if I want to stay on these drugs at all, know what I mean? Was on Paxil for a couple of years - made me kinda bummed out for stretches - emotions strange - no tears at a funeral - felt somewhat mechanical. Taking lexapro for about a year now - weight gain, short times w/ fatigue (laziness), mini-depressions, elevated blood pressure. The 150mgs are borrowed so I could try it out - my prescription is for 300mg - why do you think so much for a beginner - I'm thinking the 150s would have been a good place to start...I don't know????? Anyhoo - I'm listening. Thanks.