I have experienced pretty bad morning sickness during weeks 6-present. I am currently 11 weeks pregnant. I vomit regularly each morning and evening, but can make it through the day as long as I eat regularly. The night is bad, in fact, it is difficult to sleep because of the constant nausea.
I took a generic of Zofran just once and thought it was a miracle drug. My nausea stopped literally within minutes of taking the Zofran. I was so happy!
However, about 3pm the same day, I began experiencing the WORST MIGRAINE of my life. I thought I was dying. I kept thinking, I must have a brain tumor or something. It hurt to breathe. I asked my husband to call the pharmacist, my doctor, everyone because I was in so much excruciating pain.
In summary, I would advise everyone NOT TO TAKE ZOFRAN!!! If you have morning sickness, trust me, that is tough but nothing compared to the severe migraine you might develop due to the drug.