One week ago I started a 10 day Biaxin 500MG 2x daily for a sinus infection. 4 days after beginning the Biaxin, I started a cough syrup with codeine. I am sleeping deeply at night, no more coughing keeping me awake, have dreams- but not nightmares, but am still tired all day long. No energy at all. My appetite has increased tremendously - which doesn't thrill me! The good news is, NO metallic taste, no stomach problems, no anxiety, etc. I will complete the rx and hope it knocks out the infection. Some are super-sensitive to meds, others just mildly affected.