Within 1/2 hour of taking 2 capsules for a headache, my mouth got sore, lips felt tingly and swollen, my tongue swelled, all extremities started aching and tingling, my insides hurt,felt like they were on fire. I was cold, covered with several blankets and curled up like a ball. Vomited once, continued hurting all over, all muscles hurt and tingled.6 to 8 hours later the mouth didn't hurt so much but the muscles still hurt...I can only describe it like the pain you get in your bones when you've stuck your hand into the bottom of a vat of icy water to get a can of pop, and pulled your hand up when you couldn't stand the cold any more. That kind of an achy pain, only all over. In the am when I got up, all was okay except for a mild aching in my forearms, hands, calves , and feet. Now, over 24 hours later, I'm fine. I would rather have had the headache.