I took Lamisil in 1999 with no problem, but then, about 6 years ago I was taking Lamisil again and had some heart issues. I was taking a multivitamin at the same time as I was taking the Lamisil. I started having severe PVC's after a few days and actually went to a heart specialist because I didn't know what was wrong. I quit taking the Lamisil immediately because I thought there may be a correlation. After about a week the PVC's stopped, but I never did start back on the Lamisil. It just so happened that a couple of months later I saw a news story that anti fungal medications can cause heart problems if taken in conjunction with vitamins. I am convinced there was a connection.