Boy i thought i was the only one and my family thought i was just making this stuff up. I have asthma and have had it since i was 10 now age 23. Recently i went to the doctor because i was using my albuterol inhaler to much i was using one a week. The doctor told me i had bronchitis now even worse so he put my advair 250/50 ive been on it for about 2 months. One week after taking it i notice my voice changed and my troat was bothering me, i was having nose bleeds. This week i started having really bad headaches my hands fall asleep at night without my even sleeping on them, also bad back pains my legs get bad cramps at night. One bad thing i really hate is i know i have gained a good mount of weight about 30lbs in so little time. My husband notice my mood swings ive been having towards him getting mad at him for no reason. Thank goodness im not going crazy seeing that im not alone. IM GONNA STOP TAKING THIS MEDICINCE AND CALLING MY DOC MONDAY MORNING!!!!1