I started taking Effexor about 1 month ago for depression instead of Zoloft. I have had headaches for the last 2 weeks, very moody, tired all the time and have no engery. I feel completely useless about myself, my depression seems to have just gotten worse since I have been on it. I have a very hard time dealing with my children, and that was never been a problem for me before. I am now trying to get off of Effexor and hoping that I don't get the bad affects of getting off of it, but I figure that it can't be any worse then the feeling that i have right now.