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I noticed a lot of postings about weight gain on Singulair, which...

Posted at 12: 7 PM on Apr 10, 2008 by hrtprice, #29414
I noticed a lot of postings about weight gain on Singulair, which is nowhere listed by Merck as a possible side effect. My 15 y.o. daughter experienced sudden weight gain at the age of 9 when she was actually underweight (BMI went from 17 to 21). To make a long story short, after being off Singulair for over a year, she is now over-weight, and diet/exercise have never made a big difference (gymnastics, swim team, figure skating, trampoline, etc.) Extensive labwork is always normal & there is no family history of obesity. It's a shame the quality of life of a child is RUINED by a drug that is deemed to have "no side effects", and the many drs. & specialists out there take it very lightly. We continually worry about our daughter's self-esteem, risk of diabetes, and other complications from weight gain which is not hereditary and goes on unexplained by the drug co. Reversing this weight gain has been nearly impossible. Everytime I hear a news report about our children being overweight and obese, it makes me angry because I think about the many kids that are taking this highly prescribed drug (for even the mildest allergy or asthma) and who knows how many parents don't make the connection!
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Reply 5 months ago on Apr 10, 2008 by flindy, #6954

Funnily enough my son was placed in a study for asthma patients and obesity,what the study outcome is going to be i dont know,but yesterday when his study cordinater called, i couldnt help myself,gave her an earful.Feeling a little guilty today,but what the hell im taking no prisoners

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Reply 5 months ago on Apr 10, 2008 by concernedcitizen, #6956

I am anticipating that once I get through looking for journal articles that there will be some kind of connection to the weight gain in Singulair and the one that many people experience on antidepressants. Probably a genetic component again because montelukast pathways involve genetic variants.

http://www.nature.com/npp/journal/v28/n3/abs/1300027a.html

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Reply 5 months ago on Apr 10, 2008 by cheflette, #6961

concernedcitizen! i never would have made the connection that way without reading your reply here, but of course you're probably right about the weight gain being linked to the havoc singulair wreaks on the brain. that opens a whole different can of worms! thanks for all your hard work on this!

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Reply 5 months ago on Apr 10, 2008 by dtrzaski, #6964

My 7 yr.old had also gained weight.She is about 10 pds. over for her height.Her eating habits definitely changed while on singuliar.She became obsessive about food.She was anxious,and worried that there would not be enough if she wanted seconds.This was not the norm for her.There were other compulsive behaviors that I found odd.She is getting back to herself .And the food issue,as well as the other anxieties are going away.There is no doubt in my mind that the singuliar caused this behavior.

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