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Posted at 2:50 PM on Apr 11, 2008 by conkel, #29479
Have any of you seen this site: http://www.askapatient.com/viewrating.asp?drug=20829&name=SINGULAIR - the side effects we all recently began discussing is documented from users and parents of users as far back as seven years ago! Why is it that the FDA just became concerned and Merck had no clue of these reports?? Interesting and distressing wouldn't you say?
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Reply about 1 year ago on Apr 11, 2008 by moses, #7028

I am familar with this site. I actually sent many of the comments to the FDA. I receive FDA e-mail messages on recalls, warnings etc on a regular basis.

However, I keep asking people with probems with any drugs to send an e-mail to the FDA. This is the only way they will get the message. Go to www.fda.gov and click on "Report A Problem".

Just people talking to one another will not solve the probelms, so when your writing to www.medications.com or www.askapatient.com, also drop a line to the FDA.

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Reply about 1 year ago on Apr 11, 2008 by concernedcitizen, #7033

I believe that Singulair has been very aggressively marketed since the beginning. I was just visiting the information that the public can read at the FDA website. I saw things like letters of warning that were issued to Merck because their advertising campaigns made sneaky references to things. One of them was a letter of warning about not showing a picture of a person exercising and not having asthma because at the time of that letter no studies had been done. They did some studies later.

I have much more serious concerns about montelukast that involve some early stuff that I read about liver enzyme tests that were done regarding CYP2 and some later research that I read about mast cell homeostasis, IgE, and the studies about the genetics differences in populations.

If some very prestigious experts don't take an interest in these side effects, I really don't think that the patients are going to be well served by the research and medical establishment. When I lived in Washington, DC many years ago, there were two jokes about revolving doors between the government agencies and the corporations, one was the FDA and the other was the SEC.

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Reply about 1 year ago on Apr 11, 2008 by hrtprice, #7034
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Reply about 1 year ago on Apr 11, 2008 by catherineevans, #7041
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