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Our son started taking Singulair when he was 2 for severe allergi...

Posted at 3:10 PM on Apr 24, 2008 by isobel1228, #29901
Our son started taking Singulair when he was 2 for severe allergic rhinitis and cough variant asthma (in addition to Zyrtec, which didn’t control all of his symptoms). He is 5 now. For the last three years, he has been an increasingly violent, difficult, defiant, argumentative, volatile child who has intense mood swings--one minute he’s laughing uncontrollably, the next he’s weeping over nothing. His doctor and therapist recommended that we see a psychiatrist to have him evaluated for bipolar disorder, which used to be unknown in children. Because he has such chronic sleep problems, the doctor also suggested we take him off Singulair (and increase his Zyrtec dose) to see if it improved his sleep issues. Within a week, he was sleeping much better and was a calmer, happier, gentler boy. He suddenly could take “no” for an answer without flipping out and trying to hurt me. We thought that we were just in an unusual, calm window that would shift either to mania or intense sadness or both, any minute. We also thought that his behavior change might be due to sleeping better. We were enjoying the rare reprieve. Over the last weekend, his springtime allergies really flared up. We gave him Singulair on Monday and by noon, he was completely out of control. I had to strap him into his car seat at one point to keep him from hurting either me or himself. It finally occurred to me that Singulair might be causing his “bipolar” disorder. Of course, we stopped the Singulair. After two days he was a new boy. Yesterday, I Googled “Singulair bipolar children” and got a few hits. I am stunned to read how similar other families’ experiences have been to ours and I feel sick that we gave this drug to our child for three years.
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Reply 5 months ago on Apr 24, 2008 by swaldron, #7582

Our son had the same symptoms when on Singulair. And our doctor wanted to start him on Prozac for Bipolar disorder. We then heard about the link between Singulair and behavior problems. (We had brought this up to the 9 different doctors that we took our son to and they all said we were crazy. Medicine would not cause the behavior changes.) But we have taken our son off the Singulair and have seen a great improvement. He is even going back to school after not going for most of the year due to anxiety disorder.
These doctors are just not open to listening to most parents. They think we are all just making excuses for ill disciplined children.

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Reply 5 months ago on Apr 24, 2008 by concernedcitizen, #7583

Do you have a family history of either hypoglycemia or diabetes? I am pursuing this idea for a while until I rule out a possible link.

Here is an article about genetic hypoglycemia.

http://www.medicalnewstoday.com/articles/43988.php

The Chinese researchers showed that the cysLT1 (singular) receptor appeared in their tests after the brain had experienced stress caused by oxygen/glucose deprivation. I went back to look at the 1999 studies and they did not know it existed in the brain. Either they didn't look or they didn't know that it would appear when the brain was stressed.

It must have some function if it appears when the brain is deprived. If the receptor is blocked by montelukast (singulair), then something doesn't happen that should be happening. The bad behavior could be nothing more than depriving the brain of the function of that receptor which gives signals to the body to fix the problem with lack of oxygen/glucose.

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Reply 5 months ago on Apr 24, 2008 by cheflette, #7591

hi all. we had the bipolar diagnosis too. and the doctors all saying of course it wasn't singulair.

CC, no history of either in our family on either side that we know of.

Lisa

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Reply 5 months ago on Apr 24, 2008 by kristina551980, #7596

my son also has a poss. bipolar dx but he even had it b4 the singulair But I looked back & saw he was on claritin at the time when they were thinking he had bipolar So does claritin have simliar S/E's IDK??? I have to assume so at this point

CC no hx of either in our gamily either sorry
we do have family hx for mental illness though on my son's dad side Not mine
HTH

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Reply 5 months ago on Apr 24, 2008 by concernedcitizen, #7602

A lot of think about in this article.

"While it cannot be denied that mental illness does afflict children, and that its significant impact on both the children and those around them cannot be dismissed, the soaring figures need to addressed. Too many children are falling victim to a labelling system that is increasingly based on what has been termed ‘shoddy science’, and harmful drugs, with their lure of a quick-fix solution, have become the first port of call.

Unless this situation is taken in hand, this sweeping epidemic of medicalising behavioural problems of otherwise healthy children will only serve to fatten Big Pharma’s wallet."

http://www.wddty.com/03363800369576166173/psychiatric-labels-an-epidemic-in-children-s-mental-healthcare.html

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Reply 5 months ago on Apr 25, 2008 by concernedcitizen, #7614

I found a list of medications that a poster put up as an example of everything they were taking for their symptoms. The poster has had asthma for 30 years. Then at some point, unstated, became bi-polar. I am flabberghasted about this list. How can anyone's liver process all this stuff? Is this common that doctors will just keep prescribing for one symptom after another with a new med? This poster claimed that the number of meds had steadily increased over the years. In the old days, a doctor would have been called a Quack for prescribing all this stuff.

Theophlline 300mg twice daily for asthma and COPD
Nexium 40mg in the morning for acid reflux
Atenolol 25mg in the morning for high blood pressure
Lexapro 10mg twice daily for depression
Synthroid 0.075 mg for hypothryroid
Klonopin 1mg three times a day for anxiety
Xanax 1mg as needed for severe anxiety attacks
Advair 500/50 twice daily for COPD
Singulair 10mg once a day for allergies
Spivira once a day for COPD
Benedryl for allergies every 4-6 hours as needed for allergies
Albuterol inhailer every 4-6 hours as needed (rescue inhailer)
One 81mg asprin daily ( for blood flow to the brain)
Vicodin 10/660 every 6 hours times a day for pain L-spine
Lamectal 100mg at bedtime for Bipolar

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Reply 5 months ago on Apr 25, 2008 by cheflette, #7625

CC i don't know how doctors get away with this, but i will tell you that my husband was dx with mild bipolar disorder three years ago and he takes lithium, klonopin, cymbalta, and lamictal. previously he was on several other drugs at once, which caused intense migraines. the new, GOOD, doctor put him on these and he's been stable ever since, but it scares me how much he takes. and i'm sure he'd be taking a pile more if he had asthma, allergies, high blood pressure, high cholesterol, and whatever else the poster you quoted has. my 3/4 year old son was prescribed SIX different medications for allergies alone (we didn't give them to him because the thought of it made us uncomfortable, and that was even before our singulair experience). as a family, besides my husband's above-listed medications, we hardly take any medications now, but my parents take just about everything they are prescribed. my favorite is the antibiotics for viral illnesses.

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