I went on Prednisone for only 3 days as treatment to a bad allergic reaction to antibiotics. I ended up in the ER for treatment of the allergic reaction and they gave me a pred IV. They put me on 80 mg tablets, which I was supposed to take for 5 days, but there was no tapering off called for by the doc. I only took it for 3 days and started bad abdominal cramps and a bad taste in my mouth. Everything tasted extremely salty--and still does almost a week later. After I was off the drug for a day or two I started bad cramping in my chest, trouble breathing even though they said my lungs were clear, and really bad anxiety, which I've never had before. I freaked out while I was driving and had to pull into a parking lot for over an hour, and still had bad anxiety trying to drive home. I felt like I was drowning and had labored breathing. It's been almost a week and I still have muscle cramping in my chest, but it's starting to subside if I stay calm. I now have headaches and am weak generally, but am starting to come out of it, I think. I don't think the docs wanted to admit that lot of this was due to the pred; it is a serious drug that should not be taken lightly. I never knew there could be such extreme side effects to a drug. I am sorry to hear that many of you have had similar experiences, but it does give me some comfort to know that these effects were real and not due to some psychosomatic problem.