mmm, contrary to virtually all the previous comments, I don't seem to have any adverse reaction to Flomaxtra. I had complete urinary retention, that required insertion of a catheter. My psa is normal, and my prostate size is typical for age. Flomaxtra was suggested as an alternative to surgery. Flow has increased from zero prior to taking the medication, to 12-15cc/second after about 2 weeks . (I am 54 years old). I have been on Flomaxtra for 6 weeks now . The only physical change I have noticed, is an increase in penis size, likely due to relaxing of muscle. Ejaculation and erection is normal. I do not like taking drugs, and will monitor any changes, but life is one hell of a lot better than not being able to pee, and catheters are so dehumanizing.