i've been taking Welchol - 2 tabs morning and 2 at night - As with the statins, the muscles in my upper arms hurt so bad that I can't sleep, can hardly hold the leash to walk my dog and NOW (after taking Welchol) I am getting pain in my foot and knee. My doctor may get angry but I don't care, I'm not taking anything else for this....I'm 52 and living with daily pain and why should I? I could live pain free simply by stopping this mess.....so I am....stopping that is.