My Premarin does not seem to be working at all. My hot flashes are back and my hair is thinner and thinner. It does cause this problem with hair but I'd rather not be dripping 2-3 x a day! My doctor says to keep taking it as it has worked in the past. I checked into www.safetyalerts.com and found that the drug manufacturer has recalled many dosages for failure to dissolve. No wonder it doesn't work!