This is also a follow up. My daughter 11 was put on Singular 4 years ago. The first symptom we noticed was the rubbing for her thumb abd fingers. We thought that it was anxiety because i had recently been hospitalized. For the past 4 years we have attributed most of her symptoms tp PANDAS. She also found out recently that she has high cholesterol. All of these kids having the same side effects can not be a coincidence. I will file a report with the FDA. We took her off of it about 1&1/2 weeks ago and have seen definite improvement. With everything she's been through I'm sure that she's continue to need support even after this medication gets out of her system.