My wife started on 6.25 dosage for her inability to sleep properly. It helped her sleep. However, the 6.25 stopped being responsive and her MD prescribed her a higher dosage. Once she started taking the higher dosage, her thought process was impaired and had extreme pressure headaches along the head, face and neck. Her mind was so screwed up that she started to have suicidal thoughts and intense feelings of fear that she would start to have panic attacks. I do not know how these drugs get FDA approved. Went to a naturopath who did a hormone test and found that her hormones were unbalanced. Went on bio-identical hormone replacement therapy and she is herself again. She is also able to sleep properly.