I am just starting (hopefully) to come off the Medication Ride From Hell. I I am 61 and take estrogen, diovan, vytorin, boniva, and just started back taking Prozac (1/2 dose) after this fiasco. Two weeks ago today I started having pain in my face like I got hit by a MACK truck for 5 days, especially one tooth hurt if I touched it. Then on Tues, I went to dentist, took x-ray, no abscess. So figured sinus infection. Wed I go to have epidural shots in my back for 3 bulging discs. But I had a slight fever and suspected sinus infection, so they would not do an epidural, for fear of introducing bacteria into my spine which could result in paralysis. OH BOY So this doc gives me tramedol 50 mg for pain in 3 of my discs. Eventhough 2 ibuprophens work great, I can't take advil because of stomache issues. I am sensitive to meds, so a little goes a long way. So then back to my reg doc who gives me AVELOX . And now the nightmare begins......At 7:30 pm I took Avelox and 1/2 half of a tramadol (never took either one before). Around 9:00 pm took another 1/2 tramadol. Figured I was tolerating well. At 1:30 a.m. took a whole one. (RX is 1-2 3 times a day) A few hours later I wake up itching all over. By 5:30 a.m. the slightest move I make I am spinning and nauseous. Fall back to sleep, get up and am having vertigo and nausea. I think maybe a little sprite will settle my stomach. I immediately throw it up. My body feels paralyzed with muscle spasms, pain and extreme weakness. Also pain between my shoulder blades, heart palpitations, sense of panic, extreme heaviness in my limbs, headache and continued dizziness and nausea. Felt as if I had a slab of concrete on top of my chest, as if the muscles would not move to let me breath. Call my hubby home. He takes me to urgent care, they started an IV ad then because of "possible heart symptoms" they ambulance me to the hospital. At hospital, they gave me anti nausea meds in IV. The ride in ambulance was a big blurr. My first time in 61 years ever in an ambulance. They confirmed my sinus infection with a CAT scan which probably ruled out some other things too. I leave hospital around 5 pm and am feeling somewhat better, as all meds are now out of my body for about 15 hours. Fri, no Avelox...took a break. Sat, Sun took it and all the symptoms came back except for the vertigo and nausea which was caused by the tramedol. Skipped Monday, to test theory that it is the drug. Take it Tues, within 2 hours symptoms back with a vengeance and major panic attack out of no where, hearting pounding. I am at work so I manage to get through and when I get home I collapse in chair and can't move. Finally Wed I said thats it NO MORE AVELOX. Thurs, back to doc. She gave me Bactrim DS. I am still having some muscle weakness and fatigue. Woke up at 11:30 a.m. and took pill around 2:00, fell back to sleep around 4:30 pm with spasms in upper back and shoulders, causing weakness in my arms. I hope I can tolerate the Bactrim for the next 9 days and my side effects let up. The doctors and pharmacist look at you like your crazy when you tell them what happened. When I found this site I was so relieved when other people described the same symptoms as mine down to the smallest details. Thanks for being here.