If you have any other course of treatment, take it. It has been 6 years since my last injection of Lupron. Between the ages of 26-36 I was given a total of 18 injections( 3- 6months treatments), to try and treat my endometriosis, It did not work, I ended up having my ovaries removed. I was not aware or told of the effects from the Lupron I would have(* except for TEMPORARY hot flashes and no period) to tolerste over the years. My short term memory is gone almost, I feel like an idiot most of the time. I can remember what bathing suit I had when I was five, but I can't remember a what subject I am talking about when I am on the phone or talking to a person for example. I am 43. Because of all the Lupron I was given, I had to start getting a yearly mammogram when I was 30 because of the hormones, so I get an added bonus of a 10 year head start on radiation form the x-ray machines. Besides the memory loss, I have insomnia, hot flashes, vision problems, fatigue, and LIVER problems ( I am not a drinker or a drug user). I know people would think this is a normal part of menopause, however, I have been having all of these symptoms, even with my ovaries and never had any of these symptoms until my 3rd injection of Lupron. I refuse to go on PREMARIN, (why would I want another hormone, and one made from pregnant horse urine!) If Lupron works for you, wonderful, but my doctor, said the symptoms would be gone within 4 months after my last shot. HE WAS WRONG. Good Luck