Hi I am a doctor practicing in Harley Street.
I would first like to point out how useful these message boards are. Many of these side effects such as depression were clearly NOT picked up in drug trials/testing. This is because of the very nature of the side effect, in the way that it may go unnoticed to a degree or not feel like a typical side effect one would receive from acne treatment.
However, this said i have heard of such side effects previous to this forum. Just recently i had an appointment with a young boy of 15 who reported his own noticeable mood changes after 2 months of using the drug.
I would strongly recommend any current users to visit their GP to discuss alternate options as not accepting depression as a side effect can lead to disastrous consequences.
Please get in touch if you have any more concerns - ******
Dr Mohinder F.