This comment isn't necessarily directed to the previous couple of posts; however, I did want to mention that you can conceive with Mirena. It simply decreases the chances that implantation will succeed. This is a good explanation why so many women often report feeling extremely fatigued, like the fatigue of the 1st trimester. This very thing happened to me. While I had the Mirena I was pregnant for a couple of weeks. Please let your conscience be your guide and be informed.