I was recently prescribed 500 mg of Levaquin per day (for a total of 10 days) to treat a sinus infection and a staph infection of the eye (the systemic Levaquin was in addition to Ciloxin eye drops).
I have almost always been prescribed Zithromycin for infections in the past, which I have used without incident.
All I can say is that I'm on day 7 of the Levaquin now and I'm having several very weird side effects.
I'm anxious as hell, irritable, terrible nightmares, flashes of hot and cold that seem to have nothing to do with the actual temperature of the environment. This Levaquin seems to be having effects on me that are more akin to a psychotropic drug than a regular antibiotic.
I did some research on the web and found out that fluoroquinolone antibiotics compete with GABA receptors in the brain, which means that, at least for some people, the fluoroquinolone antibiotics such as Levaquin will have an effect on them that is pretty much the opposite of valium . . . instead of calming you down . . . it ramps up your central nervous system and can seemingly cause all sorts of weird things.
At least for me, I don't think I'll be wanting to take this Levaquin drug ever again. I can't say it's bad for all people, but it's been a very unsettling experience for me.