I am 45 and on BC to help control perimenopausal symptoms. I tried BCs (including NR) a couple of years ago but had to stop because I became severely fatigued and depressed (slept through the month of November!). I'm trying BCs again, and yes, NuvaRing again. I am exhausted, can't think or remember anything, all I want to do is sleep. I have gained 15 pounds and haven't changed my eating habits at all. I noticed that some of you posted increased cholesterol levels. I have not experience this, but I have recently (3 weeks ago) been told I am anemic (B12 deficiency). I wonder if BCs can contribute to this? Any thoughts?