One 37.5 mg Effexor XR and I thought I was a dead woman. I was BURNING HOT for 12 hours. I had a massive headache and I felt like I swallowed a brick my stomach hurt so bad. I was vomiting and trembling bad. Doc said he would consider that an allergic reaction and prescribed Celexa, which took 3 days to make me hypermania and I almost called 911 when my G.I. tract started burning. So this week he gives me Cymbalta, what is he NUTS? He let me try a small amount of xanax which doesn't give me side effects, it just releases that feeling of impending doom that I have 24/7. He says I can't have any more though, it might get me addicted. I can't imagine it being worse than what I have found online about SSRI's.