My 76 year old mother began taking Levaquin for a foot infection. Seven days into the course she developed severe muscle cramps and joint pain. She has been off this drug for one week and is still stiff and sore! She said imagine having lifted a 70# barrel and that is what her shoulders and arms feel like, almost like ripped tendons. Her knees and lower legs also ache and she doesn't do regular exercise (fell and broke her back some time ago) so this med does affect people who aren't exercising on a regular basis as well.