I was taking Avandia since I found out I had Diabetes in 2000 [another story with that one]. After all the bad news that was confirmed in 2007, I switched to Metformin then to Metformin and Januvia. The first three months after taking the Januvia, my blood pressure was high and the protein level in my urine increased. I was taking the Enalipril for at least 5 years for my kidneys [not for high blood pressure]. I never had high blood pressure. My doctor increased the Enalipril and three months later my blood pressure was still high and protein level more than doubled. I think there is a strong connection because it started right after I stated taking the Januvia. Any one else have this happen?