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The arthritis/crohn’s disease drug Remicade, manufactured by Ce...

Posted at 11:16 PM on Jun 30, 2008 by lopi13, #31947
The arthritis/crohn’s disease drug Remicade, manufactured by Centocor is a deadly drug and should be taken off the market. The drug has caused death and permanent damage to patients across the world. The drug company makes billions of dollars and downplays the side effects including the increased risk of lymphoma and blood problems. The company downplays infusion-related reactions saying that those reactions usually occur within 1-2 hours post infusion. Here’s the truth: *Centocor has been reprimanded by the FDA for publishing false claims in its marketing literature given to physicians. See FDA website for official document. *The literature lists syncope (drop in blood pressure), bradycardia (slowed heartrate), pancytopenia (dangerous drop in blood cells..platelets, whit blood cells, red blood cells etc, increased risk of lymphoma, serum sickness. The literature says to call MD if you are “pale”. *Here is a case of what happened to a woman in her 30’s with rheumatoid arthritis after only the 2nd infusion. She was not on methotrexate at all so this is all Remicade’s fault. Approximately 2-3 days after the 2nd infusion the patient began to feel tired and sore but still worked an 8 hour shift that day. By 12 midnight the patient’s entire body flared up…every joint was literally swollen and she was vomiting violently.. She could barely get to a phone to call for help. Her blood pressure dropped to 50/40 and all of her blood counts plummeted. Her Sedimentation Rate (which measures inflammation had always been below 2 and it spiked to 29!!!) Remicade caused the opposite of what it was supposed to do. It also increased greatly her C-Reactive Protein which is also a measurement of inflammation and can cause cardiac inflammatory processes as well increasing the risk of cardiac damage. The nurse in the triage area told the patient that if she had not called for help SHE WOULD HAVE DIED !!! She ended up in the hospital for 5 days in an isolation room. She was in excruciating pain and had to be given Oxycontin every 12 hours and Dilaudid IV every 2 hours to control the pain. For the first 2-3 days she could not even walk or go to the bathroom without assistance. She was given high doses of prednisone to decrease the inflammatory process and get her pain under control. A hematologist performed a bone marrow biopsy which revealed an abnormal population of plasma cells that can develop into myeloma or lymphoma. The hematologist said that the patient would have to be monitored lifelong to watch the pre-cancerous cells. The patient was out of work for 3 months and was forced to change jobs because of her fatigue level and short term memory problems. She also suffered post-traumatic stress due to her near-death experience and total upheaval in her life. She is a healthcare professional. Even 4 years after the reaction her blood counts are still abnormal and she has still had short term memory problems and vision problems.
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Reply about 1 year ago on Jul 03, 2008 by stevew, #9739

I have taken Remicade with Methotrexate for over 5 years with no problems. Greatly relieves my arthritis.

Stephen Wood

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Reply 10 months ago on Jan 14, 2009 by mscsalto, #15977

I have taken remicade for 7 years without any problems. It is the only thing that helps my UC. I am fully aware of the side effects, which most people are, if you cannot handle the possibility of these side effects then don't take it. Its not for everyone, I am perfectly aware that I can get Lymphoma, it is NOT downplayed AT ALL! A good doctor always makes someone aware, the link to cancer has been known as long as I have been taking it. People who are sick should be aware that they can die, the post traumatic stress is such an annoying cop out, get over it, many other people are worse off. Simple case of pity seeking. Did she not sit next to dying cancer patients like I do every 6 weeks? I still find my situation far better than theirs... she is still alive. I guess you don't understand how people like me are far worse off of remicade.

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Reply 3 months ago on Aug 29, 2009 by vrichard, #22619

Let me tell everyone something if you Chron's disease you keep your mouth shut
I have Chron's for over 20 yrs and I remember when there was no treatment
Remicade which I have been on for 10 yrs like other drug has it side effect. What is quality of life when your in pain 24 hrs a day. Most of these side effect or cause by the underlying disease not remicade. Anyone has the right to say yes or no to treatment. But before you want to take off the market there are some of us who love it
.

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