I was on prednisone for a little over 2 months for my asthma and it got even worse so my dosage got upped and I overdosed on it and had real bad mental side effects from it. i'm a healthy male who has worked out for the last 8 years, i'm 22 years old and 225 lbs with a good build, i workout every day and run 3 miles a day. i was taking 10 mg pills 3 times a day and then got up to taking a 50 mg pill once a day and within 2 days of taking the 50 mg pill i was HORRIBLE. the mental side effects were so bad, i didn't even know where i was or who i was at times and now it's about 5 months later and i'm still noticing the mental side effects, not quite as bad, but it's like a constant headache that never goes away. i talked to my doctor and he sad that they can last several months after you take it but won't be permanent so i'm still just living with it and at times it feels like it's rough and tough to deal with but you just have to keep thinking that it will get better. the sleeping problems can also be a problem too, but for anyone out there who is debating on taking it, I WOULD DEFINITELY NOT RECOMMEND IT, STAY AWAY AT ALL COST IF YOU CAN