horrible...started taking coumadin in November of 2007--it is now July of 2008 and in recent weeks I have had the most horrible bruising all over my body--deep maroon and deep purple and HUGE! One covers my hip on my back completely and I have others all over me. I have been having severe fatique, widespread pain to include my entire abdominal cavity, my lower and upper back, my sides, sudden headaches, and a general feeling of malaise, weakness in extremities...I am not taking this medication EVER again and I have an appt with my heart doc in a few days. I feel like I've been run over with a paver and aspirin is obviously a better choice for me. What's the use of preventing clots if your quality of life is s__t. After all, it is basically rat poison. Seriously, folks...look at the ingredients on both.