Wow! I can really relate to this website. I started taking Vytorin about 3 mos. ago. Within a few weeks, I thought I sprained my knee-went to urgent care-came out with a knee brace and crutches. Then my knee got progressively worse - and my other knee started swelling and the pain was so horrible I could hardly walk or move around. Then I got lower back pain - my physician has referred me to an Orthopedic Specialist - but I was crying so much the other nite with my pain - I literally prayed out to God to please help me. He put the thought in my head to go check the internet for side effects and I realized the only drug it could be was Vytorin. I am so grateful for finding this website. I hope and pray my muscle damage is not irreversible. This truly has been worse than anything I could ever have imagined. Thought my life was over. Just stopped taking the drug - I will never take it again.