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Over 6 years ago, the following Petition was submitted to the FDA...

Posted at 10:49 AM on Jul 21, 2008 by drmike4777, #32585
Over 6 years ago, the following Petition was submitted to the FDA, I would encourage every patient being treated with statins to read it and bring it to the immediate attention of their physician: CITIZEN PETITION TO CHANGE THE LABELING FOR ALL STATIN DRUGS (MEVACOR, LESCOL, PRAVACHOL, ZOCOR, LIPITOR, AND ADVICOR) RECOMMENDING USE OF 100-200mg PER DAY OF SUPPLEMENTAL CO-ENZYME Q10 TO REDUCE THE RISK OF STATIN-INDUCED MYOPATHIES (INCLUDING CARDIOMYOPATHY AND CONGESTIVE HEART FAILURE). http://www.fda.gov/OHRMS/DOCKETS/dailys/02/May02/052902/02p-0244-cp00001-01-vol1.pdf May 24, 2002 Petitioner: Dr. Julian M. Whitaker, M.D. This Petition is based in part on the clinical findings of Dr Peter H. Langsjoen, MD, which he also reported to the FDA: Statins kill people - lots of people - and they wound many, many more. All patients taking statins become depleted in Coenzyme Q10 (CoQ10), eventually - those patients who start with a relatively low CoQ10 levels (the elderly and patients with heart failure) begin to manifest signs/symptoms of CoQ10 deficiency relatively rapidly - in 6 to 12 months. Younger, healthier people who's only "illness" is the non-illness "hypercholesterolemia" can tolerate statins for several years before getting into trouble with fatigue, muscle weakness and soreness (usually with normal muscle enzyme CPK tests) and most ominously - heart failure. In my practice of 17 years in Tyler, Texas, I have seen a frightening increase in heart failure secondary to statin usage, "statin cardiomyopathy". Over the past five years, statins have become more potent, are being prescribed in higher doses, and are being used with reckless abandon in the elderly and in patients with "normal" cholesterol levels. We are in the midst of a CHF epidemic in the US with a dramatic increase over the past decade. Are we causing this epidemic through our zealous use of statins? In large part I think the answer is yes. We are now in a position to witness the unfolding of the greatest medical tragedy of all time - never before in history has the medical establishment knowingly (Merck & Co., Inc. has two 1990 patents combining CoQ10 with statins to prevent CoQ10 depletion and attendant side effects) created a life threatening nutrient deficiency in millions of otherwise healthy people, only to then sit back with arrogance and horrific irresponsibility and watch to see what happens - as I see two to three new statin cardiomyopathies per week in my practice, I cannot help but view my once great profession with a mixture of sorrow and contempt.
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Reply about 1 year ago on Jul 26, 2008 by mmoorstein, #10456

I took Zocor for 3 years. Prior to taking it, I was a completely healthy male 56 year old, with slightly high "bad" cholesterol level. I rode a bike a 100 miles a week and swam 3 miles a week. I had ruptured a disk (L1/S5) in my 30's (from running), but had had no problems after surgery (for 20 years).
After taking Zocor, I continued my workouts, but noticed more sluggishness and difficulty with endurance, but I chalked this up to age and slight arthritis. Nearly three years into Zocor, I found myself with terrific back pain, non-rheumatoid reactive arthritis and low-back pain. Again, I attributed this to age. I continued to bike and swim, but with more difficulty.
Approximately two months ago, I found myself getting numb in my legs and feet, with great difficulty moving. I felt that something was terribly wrong. I went to my doctor, who advised that I probably had developed spinal stenosis as a result of the progression of arthritis, especially from the old back operation. I suggested that maybe it was a reaction to the Zocor. My doctor doubted it, but suggested that I get off the Zocor to see. He indicated that I would notice a difference in 3 days if it was the Zocor. I stopped immediatly and noticed an improvement immediately. I began to read internet postings and examined drug reactions and learned about coq10 depletion and started taking supplements.
It has been less than 3 weeks, and my numbness has nearly gone, I feel looser with much more energy. I've noticed a return of libido and I've notices an ability to go much greater distances swimming and biking.
I still have some numbness in my feet and I still feel some compression pain when walking, but the distance walking has gone from 100 yards at its worse, to almost a mile when I start out. I'm using NSAIDs still (which help greatly) and have started using a cold pack (which also helps). I'm taking vitamin C.
While statins may help some, I feel Zocor nearly crippled me. I have no ideal how long the remaining numbness will continue, but I feel better every day and I no longer have the severe morning stiffness. My advice as a layman: Severely restrict the use of statins. Mark M

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