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I took this medication as a malarial prevention whilst traveling ...

Posted at 2:13 AM on Jul 26, 2008 by cbc333, #32741
I took this medication as a malarial prevention whilst traveling through India. Never EVER again. My boyfriend had suffered from depression in the past and we had heard bad things about Larium in relation to anxiety and insomnia so we specifically asked our doctor for the malarial tablets with the least amount of side effects associated with that kind of stuff. He reassured us that there was no record of Doxcycline ever having caused those sorts of effects. So off we went- we followed the instructions exactly and began our trip. A week or so into India I began to notice shortness of breath and stomach pain- I put it down to typical India travelers upset and thought no more about it. A bit later I began to suffer moments of anxiety that were really out of character ( I've never suffered from anxiety or depression). I'm very well traveled ( I work in the travel industry and have traveled extensively in the Americas, Africa, Australasia and se Asia) and so although this was my first trip to India- i knew my anxiety had nothing to do with India itself. ( people kept telling me this but I loved India) It came to a head on a overnight bus from Goa to Hampi- I was feeling really anxious, sweating and clammy, I couldn't sleep and my breathing was really tight. Eventually I had a full blown panic attack that was almost like a out of body experience- I couldn't see and I couldn't breath. The whole bus had to stop ( embarrassing!) at 3am in the morning. Eventually I managed to get back on and make it to the next town ( although not as far as Hampi) so we could take stock. I was petrified and had no idea whatsoever what was going on. It never occurred to me it could be the malaria tablets as we had been so clear and our doctor so confident they didn't have these kinds of side effects. I was worried about being on buses, trains even planes again since I didn't know what caused the attacks and I was terrified another one would happen. I had no valium or any other sort of thing that might have helped. In the end we had to cut our trip short and make it back to Mumbai - In Mumbai I suffered from another two panic attacks- one where I could see the walls closing in in our cheap hotel room. Shortness of breath, tightness all through my body, hysteria, blurry vision - it was awful! And also this ongoing pain and upset in my stomach. I ended up cutting short a RTW trip that my boyfriend and I had been saving for for over a year and coming home to Australia 2 months early. It was devastating and I still had no idea what was causing it. Finally a friend said her doctor had mentioned sleeplessness and anxiety as a rare side effect of this drug when she was taking it for some problems to do with vaginal bleeding and spotting. I started searching on the internet and was amazed to find loads of sights with people experiencing heaps of the side effects that I'd been told were never a problem with this drug! Obviously Malaria is really serious but if I had been properly informed I could have made the decision to come off the drugs and look at alternate medication. For now - Im taking the risk of no malaria tablets at all for my next couple of trips (to Borneo- so not a major risk anyway) and will actually research much harder before taking anything again!
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Reply about 1 year ago on Sep 06, 2008 by lhb7pi, #12069

I am so relieved to read your story. I was prescribed Doxy some years ago as a propphylactic for an infection. After about the 4th day of taking it, I developed traveling cold flashes. I had no idea what the symptoms were about. Then it developed into full blown anxiety and inability to sleep. I called the doctor next morning and were told these were not classic Doxy symptoms but if I was uncomfortable, to stop taking it. I actually had a full-blown panic-attack after I was off of the med for a few days. No one would believe it was attributable to Doxy especially since I was off of it for a few days. But my instinct tells me it probably was. Prior to this experience, I had never experienced panic attack before. I thought I was going to die. My heart raced to 100/min. and had terrifying cold-flashes engulfing my whold body, it felt like I was going through hyperthermia. Throughout all that no health-care practitioner would admit any of this could be attributed to Doxycycline. I feel my instincts are validated after reading your posting as well as some others. There seems to be a significant number of people that suffered from anxiety -related symptoms fromthis drug.

I've recently took one-dose of 200 mg of Doxy for prophylactic for lyme disease. I felt comfortable because it was just one dose and I made it through okay. But now I know, I should definitely avoid this particular antibiotic if I needed to be on it for a full course of a week or more.

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