I just had my 40th birthday and I've had the mirena for a year and two months now. From the beginning I started gaining some weight that I could not shake off. I've always been 125 lbs but I got up to 133 which may not seem like a lot but I was pudgy all around my stomach area. Anyway, I actually thought I was starting to go thru perimenopause. I've been getting anxiety, depression, mood swings, acne, itchy, brain fog, longer periods, ovarian cysts and I saw my primary doctor today and told her I can't take it anymore. She actually told me to consider having the IUD removed. After reading all of these blogs I'm having it removed 8/5/08. I feel better knowing that I'm not going crazy. Thank you Ladies for writing about what's really going on.