After my vasectomy I developed a horrible infection called epididymo-orchitis which is extremely painful accompanied by horrible swelling of the testicles. The ER Dr. put me on 500mg of levaquin once a day for 14 days. I am on day 6 of the antibiotic and for 2 days now I am experiencing extreme abdominal pain to the point of crying and collapsing, sever diarrhea but feels like I can't empty my bowels which makes the abdominal pain worse. Until I read some of these other stories I didn't realize that my knees and hands ache like I have horrible arthritis may be due to this med. I would much rather deal with the pain and swelling of my testicles than the side effects of this drug.