I took biaxin for 10 days in early June for a sinus infection. The side effects I noticed at the time were the yucky taste in my mouth and extreme fatigue. However, I also lost my sense of smell. It's been almost two months, and now I can smell some things, like ground coffee or ammonia, but not the more subtle scents, like flowers, light cologne, etc. At the time I was taking the drug, I discovered I couldn't smell vinegar; now I can smell it faintly. I visited my nurse practitioner yesterday, and she thought it might be a residual effect of the biaxin, but didn't find anything about loss of smell as a side effect. She advised me to wait one more month, and if the sense of smell hasn't returned by then she'll refer me to an ENT specialist. I'm just wondering if anybody else has noticed a loss or change in their sense of smell. (Smell and taste are closely related, so it's logical that it could be a result of the biaxin, since I experienced the yucky taste that so many people complain about.)