Macrobid was the 3rd antibiotic I was prescribed for a UTI because the side effects of the others were so bad. Took 1 pill in the p.m., woke the next morning with the worst nausea and pain in my neck and shoulders. By the end of the day my lymph nodes were swollen, could hardly move my head. Stayed home the next day I was so sick. The "cure" was worse than the UTI!