I too was given 20 days of 750 mg each of Levaquin and felt a pop in my shoulder while rolling over in bed and not have intense pain there which is probably my rotator cuff tear. But I also experience the most crippling intense pain to both my knees and lower back. My knees felt swollen and very painful to where I couldn't even get out of a chair, climb steps , sit on the toilet. I am a paramedic and am seriously considering leaving this job after over 25 years due to this pain. I have had some minor dizziness and some mood swings. I went to the doctor after being off Levaquin for 1 week and told her of my symptoms and she put me on a Prednisone pack which has helped me with my back and knee pain to the point where I can walk with little pain but it didn't help my shoulder pain with decrease strength in it. I don't know yet if this is a permanent cure for my knee pain or back pain. As far as my shoulder, I believe that I tore the rotator cuff and will need surg. I have also heard that prednisone is not good to take with levaquin. I was prescribed prednisone prior to taking levaquin and wonder if that started all the problems. AND OF COURSE MY DOCTOR DID NOT TELL ME OF THE SIDE EFFECTS WHEN EITHER OF THESES DRUGS WERE PRESCRIBED. But at this point, trying prednisone after completing the levaquin DEFINITELY helped my knee pain.