I am now weaning off of Wellbutrin after 4 months - I was taking it to quit smoking (I had just been through a very stressful divorce and I was smoking way more than normal.) I did not experience most of what has been discussed here (negative side effects) except for mild headaches. I am posting this simply to tell the few people who have experienced the headaches that I believe this will go away. I (like a dummy) told myself I'd only take 150mg a day rather than the whole 300mg my doctor had prescribed. This didn't work - I needed the whole 300mg, taken at 150mg doses at exactly 12 hour intervals (this makes a huge difference!) About two weeks after beginning this med, I experienced feelings of euphoria (which were quite pleasant!) but feel like I balanced out within a month. One other side effect was a change in menstrual cycle - I'm normally exactly 28 day-predictable, but missed every other month in the four months I've been on this (coincidence? Not sure...) I also drink beer nearly every night (2-4 bottles, sometimes none, sometimes more) and never had any type of seizures. Bottom line...this drug definitely helped me cut way back on smoking - I am a stress smoker and since this alleviated my stress, I didn't smoke hardly at all. Now that I'm weaning off (and yes, I did cut pills in half and have not experienced anything bad) I am curious to see if my desire to smoke will return.
Just wanted to post this out there for anyone who has had similar side effects. Overall, I have been very happy with this drug (but have never taken other Anti Depressants, so can't compare with others).