I saw an elderly ENT who prescribed Biaxin XL 1000mg/once per day for a severe sinus infection of the ethmoid, maxillay and frontal sinuses. I was not getting any better, in fact I was getting worse. I decided to go for a second opinion and learned that Biaxin is not as wide spectrum of an antibiotic as Augmentin is for sinus infections. The key strains of bacteria are not being obliterated from the Biaxin. MDs who prescribe Biaxin are not staying on top of current literature as Biaxin was commonly prescribed in the 1980s and 1990s.
My incredible side effects to Biaxin XL (including not wiping out the bacteria) include: lingering bad bitter taste, night sweats, insomnia, extreme stomach cramping, constant stomach churning (which kept me up at night), terrible diarrhea, nausea. The only plus side is that was more mentally alert.
If your doctor prescribes Biaxin for sinusitis, leave that doctor immediately and seek help from another practitioner who is more current on medications of choice for treatment.