I've had 3 Kenalog injections- one each Spring for the past 3 years for severe allergies. The injections cleared up my allergies almost immediately, and lasted the whole year. The first two years I did not have any side effects, however the third year I got a large dimple in my skin at the injection site, and it is discolored (lighter than the rest of my skin). The dimple seems to have gotten larger over the last several months since the time of the injection (March). It is approx. 2 inches wide and looks like a large scar.