I've been on Lisinopril-HCTZ for about 9 months now. I stumbled across this website because I was wondering if perhaps increased heart rate was a possible side effect. Wow, was I surprised to see all the other side effects! I haven't experienced a single problem myself. I've been a recreational runner for quite awhile, and decided to run a half-marathon a few months ago. My average heart rate during the entire race was 188. During training, it's not uncommon for my heart rate to be in the 190-195 range, which seems a little high for my age (34). Resting heart rate is around 55, so that's not a problem. I think it's highly unlikely that my high heart rate while exercising is caused by the Lisinopril.